Disabling Microsoft Exchange Content Filtering

When using MS Exchange with an outside email filtering service, you should disable Content Filtering and Sender ID on the Exchange server.  All of the filter types are enabled by default, and if the server's mail traffic is filtered by MailRoute, it is not necessary to keep them enabled.  

Microsoft announced that on November 1, 2016, they would stop updating their Content Filtering definitions, so disabling this feature is probably the safest way to avoid false-positives. See:
https://technet.microsoft.com/en-us/library/bb124739(v=exchg.160).aspx

The exact steps to take to disable Content Filtering and SenderID differ based on your version of Exchange. Here are links to Microsoft's documentation for each:

Exchange 2016:
Configuring Content Filter: https://technet.microsoft.com/en-us/library/bb124739(v=exchg.160).aspx
Configuring SenderID: https://technet.microsoft.com/en-us/library/aa997136(v=exchg.160).aspx

Exchange 2013:
Configuring Content Filter: https://technet.microsoft.com/en-us/library/aa995953(v=exchg.150).aspx
Configuring SenderID: https://technet.microsoft.com/en-us/library/aa997136(v=exchg.150).aspx

Exchange 2010:
Configuring Content Filter: https://technet.microsoft.com/en-us/library/aa995953(v=exchg.141).aspx
Configuring SenderID: https://technet.microsoft.com/en-us/library/aa997136(v=exchg.141).aspx

Exchange 2007:
Configuring Content Filter: https://technet.microsoft.com/en-us/library/aa995953(v=exchg.80).aspx
Configuring SenderID: https://technet.microsoft.com/en-us/library/aa997136(v=exchg.80).aspx

Once you disable SenderID, you should see this issue go away.

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